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Shinichi Oka Selected Research

HLA-B Antigens (HLA-B)

11/2021Collaboration of a Detrimental HLA-B*35:01 Allele with HLA-A*24:02 in Coevolution of HIV-1 with T Cells Leading to Poorer Clinical Outcomes.
10/2018Impact of a single HLA-A*24:02-associated escape mutation on the detrimental effect of HLA-B*35:01 in HIV-1 control.
7/2015Different Effects of Nonnucleoside Reverse Transcriptase Inhibitor Resistance Mutations on Cytotoxic T Lymphocyte Recognition between HIV-1 Subtype B and Subtype A/E Infections.
4/2014Molecular basis of a dominant T cell response to an HIV reverse transcriptase 8-mer epitope presented by the protective allele HLA-B*51:01.
2/2013Distinct HIV-1 escape patterns selected by cytotoxic T cells with identical epitope specificity.
12/2012Differential clade-specific HLA-B*3501 association with HIV-1 disease outcome is linked to immunogenicity of a single Gag epitope.
10/2012HLA class I-mediated control of HIV-1 in the Japanese population, in which the protective HLA-B*57 and HLA-B*27 alleles are absent.
7/2010Long-term control of HIV-1 in hemophiliacs carrying slow-progressing allele HLA-B*5101.
2/2010Selection of escape mutation by Pol154-162-specific cytotoxic T cells among chronically HIV-1-infected HLA-B*5401-positive individuals.
4/2009Adaptation of HIV-1 to human leukocyte antigen class I.
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Shinichi Oka Research Topics

Disease

77Infections
05/2024 - 04/2002
31Acquired Immunodeficiency Syndrome (AIDS)
11/2022 - 01/2002
23HIV Infections (HIV Infection)
11/2023 - 01/2002
16Disease Progression
11/2021 - 04/2002
10Body Weight (Weight, Body)
02/2023 - 08/2006
10Stroke (Strokes)
07/2022 - 11/2016
8Syphilis
11/2023 - 01/2015
8Stomach Neoplasms (Stomach Cancer)
05/2023 - 12/2017
8Hepatitis C
02/2020 - 04/2002
7Neoplasms (Cancer)
01/2024 - 02/2007
7Pneumocystis Pneumonia (Pneumocystis carinii Pneumonia)
02/2022 - 08/2009
6Sexually Transmitted Diseases (Sexually Transmitted Disease)
11/2023 - 05/2008
6Lymphoma (Lymphomas)
02/2014 - 09/2003
5Hemophilia A (Haemophilia)
04/2024 - 06/2011
5Inflammation (Inflammations)
01/2023 - 01/2016
5Spinal Cord Injuries (Spinal Cord Injury)
07/2022 - 10/2016
5Fibrosis (Cirrhosis)
01/2021 - 06/2011
5Hepatitis B
12/2019 - 03/2013
5Kaposi Sarcoma (Kaposi's Sarcoma)
01/2019 - 09/2006
5Retinitis
02/2015 - 01/2002
5Hypersensitivity (Allergy)
04/2014 - 01/2007
4Brain Ischemia (Cerebral Ischemia)
12/2023 - 11/2016
4COVID-19
11/2023 - 10/2021
4Lipodystrophy
01/2022 - 01/2002
4Ischemia
01/2019 - 04/2013
4Viremia
01/2018 - 02/2002
4Coinfection
01/2016 - 01/2013
3Ischemic Stroke
07/2022 - 10/2017
3Opportunistic Infections (Opportunistic Infection)
02/2022 - 01/2002
3Papillomavirus Infections
01/2021 - 03/2014
3Heart Failure
09/2020 - 11/2011
3Myocardial Infarction
09/2020 - 11/2010
3Pathologic Constriction (Stenosis)
10/2019 - 04/2002
3Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
02/2019 - 10/2017
3Cerebral Infarction
02/2019 - 01/2018
3Chronic Renal Insufficiency
07/2018 - 01/2013
3Anemia
01/2017 - 07/2005
3AIDS-Related Lymphoma (Lymphoma, AIDS Related)
08/2013 - 04/2006
3Necrosis
01/2012 - 09/2006
3Lactic Acidosis
05/2007 - 04/2002
3Vaccinia
11/2005 - 06/2003
2Headache (Headaches)
05/2024 - 01/2006

Drug/Important Bio-Agent (IBA)

22EpitopesIBA
11/2023 - 06/2003
21Tenofovir (Viread)FDA Link
11/2023 - 01/2011
14HLA-B Antigens (HLA-B)IBA
11/2021 - 01/2005
12Ritonavir (Norvir)FDA Link
07/2018 - 08/2002
11VaccinesIBA
12/2019 - 06/2003
10RNA (Ribonucleic Acid)IBA
04/2024 - 09/2003
8Proteins (Proteins, Gene)FDA Link
01/2023 - 06/2002
7Emtricitabine (Emtriva)FDA Link
11/2023 - 01/2013
7Peptides (Polypeptides)IBA
01/2022 - 06/2003
7Reverse Transcriptase InhibitorsIBA
09/2021 - 08/2003
7Protease Inhibitors (Protease Inhibitor)IBA
09/2021 - 01/2013
7HLA-A Antigens (HLA-A)IBA
01/2019 - 05/2005
6Darunavir (Prezista)FDA Link
09/2021 - 03/2012
6LopinavirFDA Link
09/2021 - 08/2002
6Atazanavir Sulfate (Reyataz)FDA Link
09/2021 - 01/2013
6Antiviral Agents (Antivirals)IBA
02/2020 - 05/2007
5DNA (Deoxyribonucleic Acid)IBA
01/2022 - 12/2005
5HLA-C Antigens (HLA-C)IBA
01/2022 - 07/2015
5HLA Antigens (Human Leukocyte Antigens)IBA
01/2022 - 11/2005
5abacavir (Ziagen)FDA Link
09/2021 - 02/2008
5Adrenal Cortex Hormones (Corticosteroids)IBA
01/2017 - 01/2002
4Immunoglobulin G (IgG)IBA
04/2024 - 10/2021
4Hepatitis B Surface Antigens (HBsAg)FDA Link
04/2024 - 01/2018
4tenofovir alafenamideIBA
08/2023 - 06/2015
4HLA-B57 antigenIBA
11/2022 - 04/2009
4elvitegravirIBA
09/2021 - 06/2015
4Rilpivirine (TMC-278)IBA
01/2021 - 10/2016
4CreatinineIBA
01/2021 - 01/2011
4Therapeutic UsesIBA
01/2021 - 11/2016
4Sirtuin 1IBA
11/2014 - 11/2010
4SteroidsIBA
01/2013 - 01/2006
3Interleukin-6 (Interleukin 6)IBA
04/2024 - 10/2006
3RacivirIBA
11/2023 - 01/2013
3Amoxicillin (Wymox)FDA LinkGeneric
11/2023 - 07/2015
3Probenecid (Benemid)FDA LinkGeneric
11/2023 - 07/2015
3Azithromycin (Zithromax)FDA LinkGeneric
10/2021 - 01/2019
3NucleosidesIBA
09/2021 - 05/2007
3HLA-B*52:01 antigenIBA
01/2021 - 01/2017
3lamivudine drug combination abacavirFDA Link
01/2020 - 03/2012
3ReaginsIBA
01/2020 - 07/2015
3CobicistatIBA
06/2019 - 06/2015
3Protein Isoforms (Isoforms)IBA
01/2019 - 01/2013
3AIDS VaccinesIBA
01/2019 - 03/2009
3Formaldehyde (Formol)FDA Link
06/2018 - 01/2017
3ParaffinIBA
06/2018 - 01/2017
3InterferonsIBA
01/2018 - 06/2011
3Stavudine (Zerit)FDA LinkGeneric
12/2017 - 01/2014
3Ribavirin (Virazole)FDA LinkGeneric
01/2017 - 04/2002
3Illicit Drugs (Recreational Drugs)IBA
02/2014 - 01/2013

Therapy/Procedure

72Therapeutics
01/2024 - 04/2002
20Intravenous Infusions
12/2023 - 10/2016
20Highly Active Antiretroviral Therapy (HAART)
09/2021 - 01/2002
12Art Therapy
06/2022 - 01/2012
6Gastrectomy
05/2023 - 07/2017
6Drug Therapy (Chemotherapy)
12/2022 - 02/2014
3Gastroenterostomy
02/2022 - 01/2018
3Stents
10/2019 - 09/2005
3Transplantation
06/2011 - 03/2011